个人简介：

李姗姗，博士，副教授，硕士生导师。2018年9月获南京大学分析化学博士学位，师从陈洪渊院士、徐静娟教授；2018年11月以四层次特聘教授入职青岛大学工作。主要从事生物传感器的构建和多功能纳米探针的设计开发，主持国家自然科学基金、山东省自然科学基金、南京大学生命分析化学国家重点实验室开放基金和青岛大学特聘教授人才项目各1项，参与国家自然科学基金面上项目2项，参与山东省高等学校青创科技计划创新团队1项，在Chem. Sci., Anal. Chem., TrAC Trends Anal. Chem., Chem. Eng. J., Biosens. Bioelectron., Sensor. Actuat. B Chem.等期刊发表SCI论文42篇，其中第一作者/通讯作者论文27篇，2篇入选ESI高被引论文。2023年和2024年分别荣获青岛大学优秀研究生指导教师和青岛大学优秀硕士学位论文指导教师，作为指导教师指导学生获得国家级、省级各类竞赛奖励3项。

研究方向：

重大疾病标志物检测

病原微生物相关检测

主持科研项目：

1. 国家自然科学基金青年科学基金项目（22004076）

2. 山东省自然科学基金青年基金（ZR2020QB100）

3. 南京大学生命分析化学国家重点实验室开放基金（SKLACLS1906）

4. 青岛大学特聘教授人才项目

代表性科研论文：

1. He-Nan Sun1, Miao Wang1, Xing-Yu Liu, Lin-Xiao Zhao, Shan-Shan Li*. Electrochemical ratiometric biosensor based on 2D flower-like Co/Ni MOF and sea urchin-like PdCuNi for accurate quantification of alpha-fetoprotein. Chemical Engineering Journal, 2024, 499, 156248.

2. Tong Wang, Hong-Sheng Tan, Lin-Xiao Zhao, Mingjun Liu, Shan-Shan Li*. A novel ratiometric aptasensor based on SERS for accurate quantification of cardiac troponin I. Sensors and Actuators B: Chemical, 2024, 412, 135804.

3. Tong Wang, Hong-Sheng Tan, Ai-Jun Wang, Shan-Shan Li*, Jiu-Ju Feng*. Fluorescent metal nanoclusters: From luminescence mechanism to applications in enzyme activity assays, Biosensors and Bioelectronics, 2024, 257, 116323.

4. He-Nan Sun, Miao Wang, Hong-Sheng Tan, Hui-Ping Liu, Mingjun Liu, Shan-Shan Li*. Ratiometric electrochemical immunoassay based on 2D Co/Fe MOF decorated with toluidine blue and Fc-labeled Schiff base for accurate assay of alpha-fetoprotein in clinical serum. Talanta, 2024, 273, 125876.

5. Hong-Sheng Tan, Tong Wang, Jia-Mei Han, Mingjun Liu, Shan-Shan Li*. Dual-signal SERS biosensor based on spindle-shaped gold array for sensitive and accurate detection of miRNA 21. Sensors and Actuators B: Chemical, 2024, 403, 135157.

6. Hong-Sheng Tan, Tong Wang, He-Nan Sun, Aihua Liu, Shan-Shan Li*. Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis. TrAC Trends in Analytical Chemistry, 2023, 167, 117253.

7. Yuan-Yuan Tan, Hong-Sheng Tan, Mingjun Liu, Shan-Shan Li*. Electrochemical ratiometric dual-signal immunoassay for accurate detection of carcinoembryonic antigen in clinical serum based on rGO-Pd@Au-Thi and Chi-Fc-Au. Sensors and Actuators B: Chemical, 2023, 380, 133340.

8. Shan-Shan Li, Ai-Jun Wang, Pei-Xin Yuan, Li-Ping Mei, Lu Zhang, Jiu-Ju Feng*. Heterometallic nanomaterials: activity modulation, sensing, imaging and therapy. Chemical Science, 2022, 13, 5505-5530.

9. Shan-Shan Li*, Yuan-Yuan Tan, Yan Zhang, Mingjun Liu, Aihua Liu. A simple electrochemical immunosensor based on worm-like platinum for highly sensitive determination of alpha-fetoprotein. Bioelectrochemistry, 2021, 140, 107804.

10. Shan-Shan Li, Miao Zhang, Jian-Hua Wang, Fan Yang, Bin Kang*, Jing-Juan Xu, Hong-Yuan Chen. Monitoring the changes of pH in lysosomes during autophagy and apoptosis by plasmon enhanced Raman imaging. Analytical Chemistry, 2019, 91, 8398-8405.

11. Shan-Shan Li, Qing-Ying Kong, Miao Zhang, Fan Yang, Bin Kang*, Jing-Juan Xu*, Hong-Yuan Chen*. Plasmon-resonance-energy-transfer-based spectroscopy on single nanoparticles: Biomolecular recognition and enzyme kinetics. Analytical Chemistry, 2018, 90, 3833-3841.

12. Shan-Shan Li#, Qi-Yuan Guan#, Mengmeng Zheng#, Yu-Qi Wang, Deju Ye, Bin Kang*, Jing-Juan Xu*, Hong-Yuan Chen*. Simultaneous quantification of multiple endogenous biothiols in single living cells by plasmonic Raman probes. Chemical Science, 2017, 8, 7582-7587.

13. Shan-Shan Li, Yuan-Yuan Hu, Ai-Jun Wang*, Xuexiang Weng, Jian-Rong Chen, Jiu-Ju Feng*. Simple synthesis of worm-like Au–Pd nanostructures supported on reduced graphene oxide for highly sensitive detection of nitrite. Sensors and Actuators B: Chemical, 2015, 208, 468-474.

14. Shan-Shan Li, Ai-Jun Wang, Yuan-Yuan Hu, Ke-Ming Fang, Jian-Rong Chen, Jiu-Ju Feng*. One-step, seedless wet-chemical synthesis of gold@palladium nanoflowers supported on reduced graphene oxide with enhanced electrocatalytic properties. Journal of Materials Chemistry A, 2014, 2, 18177-18183.

15. Shan-Shan Li, Jing-Jing Lv, Li-Na Teng, Ai-Jun Wang*, Jian-Rong Chen, Jiu-Ju Feng*. Facile synthesis of PdPt@Pt nanorings supported on reduced graphene oxide with enhanced electrocatalytic properties. ACS Applied Materials & Interfaces, 2014, 6, 10549-10555.

联系方式：

E-mail: lishanshan@qdu.edu.cn