个人简介：

李姗姗，博士，副教授，硕士生导师。2018年9月获南京大学分析化学博士学位，师从陈洪渊院士、徐静娟教授；2018年11月以四层次特聘教授入职青岛大学工作。主持国家自然科学基金青年科学基金项目1项，山东省自然科学基金青年基金和面上项目各1项，参与国家自然科学基金面上项目2项，参与山东省高等学校青创科技计划创新团队1项，在Chemical Science, Analytical Chemistry, TrAC Trends in Analytical Chemistry, Biosensors and Bioelectronics, Sensors and Actuators B-Chemical等国际学术期刊发表SCI论文45篇，其中第一作者/通讯作者论文30篇，2篇入选ESI高被引论文。2023-2025年荣获青岛大学优秀研究生指导教师，2023-2024年荣获青岛大学优秀硕士学位论文指导教师，毕业生中有2人分别考取南方科技大学和南京大学攻读博士学位，作为指导教师指导学生获得国家级、省级各类竞赛奖励5项。

研究方向：

重大疾病标志物检测

病原微生物相关检测

主持科研项目：

1.国家自然科学基金青年科学基金项目（22004076）

2.山东省自然科学基金面上项目（ZR2025MS241）

3.山东省自然科学基金青年基金（ZR2020QB100）

4.南京大学生命分析化学国家重点实验室开放基金（SKLACLS1906）

5.青岛大学特聘教授人才项目

代表性科研论文：

18. Zi-Wen Cui¹, Jia-Mei Han¹, Wen-Ting Zhuang, Yu-Tian Yan, Shi-Qi Ding,Shan-Shan Li*. Sandwich-like electrochemical immunosensor based on thionine-modified graphene aerogel for ultrasensitive assay of cardiac troponin I in human serum.Bioelectrochemistry, 2026, 172, 109345.

17. Lin-Xiao Zhao¹, Tong Wang¹, Jia-Mei Han, Zi-Wen Cui,Shan-Shan Li*. Magnetic separation-assisted ratiometric SERS aptasensor for precise detection of cardiac troponin I.Microchemical Journal, 2025, 219, 115891.

16. Miao Wang, Xing-Yu Liu, Lin-Xiao Zhao, Zi-Wen Cui,Shan-Shan Li*. Reliable electrochemical ratiometric sensing based on diazotization/Schiff base reaction for accurate detection of alpha-fetoprotein.Chemical Engineering Journal, 2025, 511,161916.

15. He-Nan Sun¹, Miao Wang¹, Xing-Yu Liu, Lin-Xiao Zhao,Shan-Shan Li*. Electrochemical ratiometric biosensor based on 2D flower-like Co/Ni MOF and sea urchin-like PdCuNi for accurate quantification of alpha-fetoprotein.Chemical Engineering Journal, 2024, 499,156248.

14. Tong Wang, Hong-Sheng Tan, Lin-Xiao Zhao, Mingjun Liu,Shan-Shan Li*. A novel ratiometric aptasensor based on SERS for accurate quantification of cardiac troponin I.Sensors and Actuators B: Chemical, 2024, 412, 135804.

13. Tong Wang, Hong-Sheng Tan, Ai-Jun Wang,Shan-Shan Li*, Jiu-Ju Feng*. Fluorescent metal nanoclusters: From luminescence mechanism to applications in enzyme activity assays,Biosensors and Bioelectronics, 2024, 257, 116323.

12. He-Nan Sun, Miao Wang, Hong-Sheng Tan, Hui-Ping Liu, Mingjun Liu,Shan-Shan Li*. Ratiometric electrochemical immunoassay based on 2D Co/Fe MOF decorated with toluidine blue and Fc-labeled Schiff base for accurate assay of alpha-fetoprotein in clinical serum.Talanta, 2024, 273, 125876.

11. Hong-Sheng Tan, Tong Wang, Jia-Mei Han, Mingjun Liu,Shan-Shan Li*. Dual-signal SERS biosensor based on spindle-shaped gold array for sensitive and accurate detection of miRNA 21.Sensors and Actuators B: Chemical, 2024, 403, 135157.

10. Hong-Sheng Tan, Tong Wang, He-Nan Sun, AihuaLiu,Shan-Shan Li*. Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis.TrAC Trends in Analytical Chemistry, 2023, 167, 117253.

9. Yuan-Yuan Tan, Hong-Sheng Tan, Mingjun Liu,Shan-Shan Li*. Electrochemical ratiometric dual-signal immunoassay for accurate detection of carcinoembryonic antigen in clinical serum based on rGO-Pd@Au-Thi and Chi-Fc-Au.Sensors and Actuators B: Chemical, 2023, 380, 133340.

8.Shan-Shan Li, Ai-Jun Wang, Pei-Xin Yuan, Li-Ping Mei, Lu Zhang,Jiu-Ju Feng*. Heterometallic nanomaterials: activity modulation, sensing, imaging and therapy.Chemical Science, 2022, 13, 5505-5530.

7.Shan-Shan Li*, Yuan-Yuan Tan, Yan Zhang, Mingjun Liu, Aihua Liu. A simple electrochemical immunosensor based on worm-like platinum for highly sensitive determination of alpha-fetoprotein.Bioelectrochemistry, 2021, 140, 107804.

6.Shan-Shan Li, Miao Zhang, Jian-Hua Wang, Fan Yang, Bin Kang*, Jing-Juan Xu, Hong-Yuan Chen. Monitoring the changes of pH in lysosomes during autophagy and apoptosis by plasmon enhanced Raman imaging.Analytical Chemistry, 2019, 91,8398-8405.

5.Shan-Shan Li, Qing-Ying Kong, Miao Zhang, Fan Yang, Bin Kang*, Jing-Juan Xu*, Hong-Yuan Chen*. Plasmon-resonance-energy-transfer-based spectroscopy on single nanoparticles: Biomolecular recognition and enzyme kinetics.Analytical Chemistry, 2018, 90,3833-3841.

4.Shan-Shan Li^#, Qi-Yuan Guan^#, Mengmeng Zheng^#, Yu-Qi Wang, Deju Ye, Bin Kang*, Jing-Juan Xu*, Hong-Yuan Chen*. Simultaneous quantification of multiple endogenous biothiols in single living cells by plasmonic Raman probes.Chemical Science, 2017, 8, 7582-7587.

3.Shan-Shan Li,Yuan-Yuan Hu,Ai-Jun Wang*,Xuexiang Weng,Jian-Rong Chen,Jiu-Ju Feng*. Simple synthesis of worm-like Au–Pd nanostructures supported on reduced graphene oxide for highly sensitive detection of nitrite.Sensors and Actuators B: Chemical, 2015, 208, 468-474.

2.Shan-Shan Li, Ai-Jun Wang, Yuan-Yuan Hu, Ke-Ming Fang, Jian-Rong Chen, Jiu-Ju Feng*. One-step, seedless wet-chemical synthesis of gold@palladium nanoflowers supported on reduced graphene oxide with enhanced electrocatalytic properties.Journal of Materials Chemistry A, 2014, 2,18177-18183.

1.Shan-Shan Li, Jing-Jing Lv, Li-Na Teng, Ai-Jun Wang*, Jian-Rong Chen, Jiu-Ju Feng*. Facile synthesis of PdPt@Pt nanorings supported on reduced graphene oxide with enhanced electrocatalytic properties.ACS Applied Materials & Interfaces, 2014, 6, 10549-10555.

联系方式：

E-mail: lishanshan@qdu.edu.cn